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1

Structure and function of the exocrine pancreas in patients with type 1 diabetes

Alexandre-Heymann, Laure, Mallone, Roberto, Boitard, Christian, Scharfmann, Raphaël, Larger, Etienne

Journal:

Reviews in Endocrine & Metabolic Disorders

Year:

2019

Language:

english

File:

PDF, 2.82 MB

english, 2019

2

Characterization of β cells developed in vitro from rat embryonic pancreatic epithelium

François Miralles, Palle Serup, Françoise Cluzeaud, Alain Vewalle, Paul Czernichow, Raphael Scharfmann

Journal:

Developmental Dynamics

Year:

1999

Language:

english

File:

PDF, 696 KB

english, 1999

3

Ex vivo analysis of acinar and endocrine cell development in the human embryonic pancreas

Muriel Castaing, Bertrand Duvillié, Eric Quemeneur, Annie Basmaciogullari, Raphael Scharfmann

Journal:

Developmental Dynamics

Year:

2005

Language:

english

File:

PDF, 1.08 MB

english, 2005

4

Implication of Nitric Oxide in NGF-Induced Cell Differentiation: Differences Between Neuronal and Beta Cells

Wissam Fayad, Paul Czernichow, Raphaël Scharfmann

Journal:

Journal of Neuroendocrinology

Year:

1997

Language:

english

File:

PDF, 341 KB

english, 1997

5

TGF-β activates genes identified by differential mRNA display in pancreatic rudiments

Tadej Battelino, Francisco Miralles, Ciril Kržišnik, Raphaël Scharfmann, Paul Czernichow

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 512 KB

english, 2000

6

Similarities and Discrepancies in the Signaling Pathway for Nerve Growth Factor in an Insulin Producing Cell Line and a Neural Crest-Derived Cell Line

Abdelali Tazi, Paul Czernichow, Raphael Scharfmann

Journal:

Journal of Neuroendocrinology

Year:

1995

Language:

english

File:

PDF, 1.57 MB

english, 1995

7

Dexamethasone Regulates the Expression of Neuronal Properties of a Rat Insulinoma Cell Line

Fouad Atouf, Abdelali Tazi, Michel Polak, Paul Czemichow, Raphael Scharfmann

Journal:

Journal of Neuroendocrinology

Year:

1995

Language:

english

File:

PDF, 1.06 MB

english, 1995

8

EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade

Rescan, Claude, Le Bras, Stéphanie, Lefebvre, Véronique H, Frandsen, Ulrik, Klein, Tino, Foschi, Marco, Pipeleers, Daniel G, Scharfmann, Raphael, Madsen, Ole D, Heimberg, Harry

Journal:

Laboratory Investigation

Year:

2004

Language:

english

File:

PDF, 427 KB

english, 2004

9

Long-term expression of a retrovirally introduced β-galactosidase gene in rodent cells implanted in vivo using biodegradable polymer meshes

Brian A. Naughton, Yifan Dai, Benson Sibanda, Raphael Scharfmann, Julia San Roman, Frank Zeigler, Inder M. Verma

Journal:

Somatic Cell and Molecular Genetics

Year:

1992

Language:

english

File:

PDF, 1.38 MB

english, 1992

10

proTRH gene expression by fetal pancreatic islets in culture

Sonia Aratan-Spire, Raphael Scharfmann, Ronald M. Lechan, Armen H. Tashjian Jr.

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 958 KB

english, 1990

11

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

Xiaobo Xu, Joke D'Hoker, Geert Stangé, Stefan Bonné, Nico De Leu, Xiangwei Xiao, Mark Van De Casteele, Georg Mellitzer, Zhidong Ling, Danny Pipeleers, Luc Bouwens, Raphael Scharfmann, Gerard Gradwohl,

Journal:

Year:

2008

Language:

english

File:

PDF, 1.58 MB

english, 2008

12

Specific maternal microchimeric T cells targeting fetal antigens in β cells predispose to auto-immune diabetes in the child

Edwige Roy, Michele Leduc, Sarah Guegan, Latif Rachdi, Nicolas Kluger, Raphael Scharfmann, Selim Aractingi, Kiarash Khosrotehrani

Journal:

Journal of Autoimmunity

Year:

2011

Language:

english

File:

PDF, 1.82 MB

english, 2011

13

Activating Mutations in the ABCC8 Gene in Neonatal Diabetes Mellitus

Babenko, Andrey P., Polak, Michel, Cavé, Hélène, Busiah, Kanetee, Czernichow, Paul, Scharfmann, Raphael, Bryan, Joseph, Aguilar-Bryan, Lydia, Vaxillaire, Martine, Froguel, Philippe

Journal:

Boston Medical and Surgical Journal

Year:

2006

Language:

english

File:

PDF, 708 KB

english, 2006

14

Ontogeny of two topologically distinct TRH-degrading pyroglutamate aminopeptidase activities in the rat liver

Raphaël Scharfmann, Sonia Aratan-Spire

Journal:

Regulatory Peptides

Year:

1991

Language:

english

File:

PDF, 481 KB

english, 1991

15

Development of the pancreas in medaka

Béatrice Assouline, Vân Nguyen, Sophie Mahé, Franck Bourrat, Raphael Scharfmann

Journal:

Mechanisms of Development

Year:

2002

Language:

english

File:

PDF, 288 KB

english, 2002

16

FGFR1-IIIb is a putative marker of pancreatic progenitor cells

Corentin Cras-Méneur, Raphael Scharfmann

Journal:

Mechanisms of Development

Year:

2002

Language:

english

File:

PDF, 312 KB

english, 2002

17

Functional antagonism between c-Jun and MyoD proteins: A direct physical association

Eyal Bengal, Lynn Ransone, Raphael Scharfmann, V.J. Dwarki, Stephen J. Tapscott, Harold Weintraub, Inder M. Verma

Journal:

Year:

1992

Language:

english

File:

PDF, 2.40 MB

english, 1992

18

Neonatal hyperglycaemia and abnormal development of the pancreas

Isabelle Flechtner, Martine Vaxillaire, Hélène Cavé, Raphael Scharfmann, Philippe Froguel, Michel Polak

Journal:

Best Practice & Research Clinical Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 806 KB

english, 2008

19

Dyrk1ahaploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass

Rachdi, Latif, Kariyawasam, Dulanjalee, Guez, Fanny, Aïello, Virginie, Arbonés, Maria L., Janel, Nathalie, Delabar, Jean-Maurice, Polak, Michel, Scharfmann, Raphaël

Journal:

Year:

2014

Language:

english

File:

PDF, 669 KB

english, 2014

20

Insulin, glucagon and somatostatin in fetal rat islets maintained free-floating in culture: immunocytochemistry and radioimmunoassay

Leduque, Patrick, Scharfmann, Raphael, Chayvialle, Jean-Alain, Aratan-Spire, Sonia, Basmaciogullari, Annie, Czernichow, Paul, Dubois, Paul-M

Journal:

Biology of the Cell

Year:

1992

Language:

english

File:

PDF, 12.84 MB

english, 1992

21

Signaling Through Fibroblast Growth Factor Receptor 2b Plays a Key Role in the Development of the Exocrine Pancreas

Francisco Miralles, Paul Czernichow, Keuchi Ozaki, Nobuyuki Itoh and Raphael Scharfmann

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.19 MB

english, 1999

22

TGF-β Plays a Key Role in Morphogenesis of the Pancreatic Islets of Langerhans by Controlling the Activity of the Matrix Metalloproteinase MMP-2

Francisco Miralles, Tadej Battelino, Paul Czernichow and Raphael Scharfmann

Journal:

The Journal of Cell Biology

Year:

1998

Language:

english

File:

PDF, 3.08 MB

english, 1998

23

Human Pancreas Endocrine Cell Populations and Activating ABCC8 Mutations

Busiah, Kanetee, Verkarre, Virginie, Cavé, Hélène, Scharfmann, Raphael, Polak, Michel

Journal:

Hormone Research in Paediatrics

Year:

2014

Language:

english

File:

PDF, 316 KB

english, 2014

24

DYRK1A BAC Transgenic Mouse: A New Model of Thyroid Dysgenesis in Down Syndrome

Kariyawasam, Dulanjalee, Rachdi, Latif, Carré, Aurore, Martin, Mercè, Houlier, Marine, Janel, Nathalie, Delabar, Jean-Maurice, Scharfmann, Raphaël, Polak, Michel

Journal:

Year:

2015

Language:

english

File:

PDF, 2.39 MB

english, 2015

25

Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance

Rachdi, Latif, Kariyawasam, Dulanjalee, Aïello, Virginie, Herault, Yann, Janel, Nathalie, Delabar, Jean-Maurice, Polak, Michel, Scharfmann, Raphaël

Journal:

Year:

2014

Language:

english

File:

PDF, 5.32 MB

english, 2014

26

Disruption of a Novel Krüppel-like Transcription Factor p300-regulated Pathway for Insulin Biosynthesis Revealed by Studies of the c.-331 INS Mutation Found in Neonatal Diabetes Mellitus

Bonnefond, Amélie, Lomberk, Gwen, Buttar, Navtej, Busiah, Kanetee, Vaillant, Emmanuel, Lobbens, Stéphane, Yengo, Loïc, Dechaume, Aurélie, Mignot, Brigitte, Simon, Albane, Scharfmann, Raphaël, Neve, Be

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.67 MB

english, 2011

27

von Hippel–Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulation

Soggia, Andrea, Ramond, Cyrille, Akiyama, Haruhiko, Scharfmann, Raphaël, Duvillie, Bertrand

Journal:

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

28

Ex Vivo Expansion and Differentiation of Human and Mouse Fetal Pancreatic Progenitors Are Modulated by Epidermal Growth Factor

Bonfanti, Paola, Nobecourt, Estelle, Oshima, Masaya, Albagli-Curiel, Olivier, Laurysens, Veerle, Stangé, Geert, Sojoodi, Mozhdeh, Heremans, Yves, Heimberg, Harry, Scharfmann, Raphael

Journal:

Stem Cells and Development

Year:

2015

Language:

english

File:

PDF, 3.13 MB

english, 2015

29

Role of the AMP kinase in cytokine-induced human EndoC-βH1 cell death

Fred, Rikard G., Kappe, Camilla, Ameur, Adam, Cen, Jing, Bergsten, Peter, Ravassard, Phillippe, Scharfmann, Raphael, Welsh, Nils

Journal:

Molecular and Cellular Endocrinology

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

30

Transcribing Neonatal Diabetes Mellitus

Scharfmann, Raphael, Polak, Michel

Journal:

Boston Medical and Surgical Journal

Year:

2010

Language:

english

File:

PDF, 331 KB

english, 2010

31

Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy

van der Torren, Cornelis R., Zaldumbide, Arnaud, Roelen, Dave L., Duinkerken, Gaby, Brand-Schaaf, Simone H., Peakman, Mark, Czernichow, Paul, Ravassard, Philippe, Scharfmann, Raphael, Roep, Bart O.

Journal:

Year:

2016

Language:

english

File:

PDF, 522 KB

english, 2016

32

Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans

Pal, Aparna, Potjer, Thomas P., Thomsen, Soren K., Ng, Hui Jin, Barrett, Amy, Scharfmann, Raphael, James, Tim J., Bishop, D. T., Karpe, Fredrik, Godsland, Ian F., Vasen, Hans F.A., Newton-Bishop, Juli

Journal:

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

33

Nerve Growth Factor Induces Neuron-Like Differentiation of an Insulin-Secreting Pancreatic Beta Cell Line

Michel Polak, Raphael Scharfmann, Bernd Seilheimer, George Eisenbarth, David Dressler, Inder M. Verma and Huntington Potter

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.26 MB

english, 1993

34

Long-Term In vivo Expression of Retrovirus-Mediated Gene Transfer in Mouse Fibroblast Implants

Raphael Scharfmann, Jonathan H. Axelrod and Inder M. Verma

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.09 MB

english, 1991

35

Directing cell differentiation with small-molecule histone deacetylase inhibitors: The example of promoting pancreatic endocrine cells

Haumaitre, Cécile, Lenoir, Olivia, Scharfmann, Raphaël

Journal:

Year:

2009

Language:

english

File:

PDF, 977 KB

english, 2009

36

A human beta cell line with drug inducible excision of immortalizing transgenes

Benazra, Marion, Lecomte, Marie-José, Colace, Claire, Müller, Andreas, Machado, Cécile, Pechberty, Severine, Bricout-Neveu, Emilie, Grenier-Godard, Maud, Solimena, Michele, Scharfmann, Raphaël, Czerni

Journal:

Molecular Metabolism

Year:

2015

Language:

english

File:

PDF, 1.93 MB

english, 2015

37

Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants

Thomsen, Soren K, Ceroni, Alessandro, van de Bunt, Martijn, Burrows, Carla, Barrett, Amy, Scharfmann, Raphael, Ebner, Daniel, McCarthy, Mark I, Gloyn, Anna L

Journal:

Year:

2016

Language:

english

File:

PDF, 2.42 MB

english, 2016

38

Control of pancreatic development by intercellular signals

Duvillié, Bertrand, Stetsyuk, Volodymyr, Filhoulaud, Gaëlle, Guillemain, Ghislaine, Scharfmann, Raphaël

Journal:

Biochemical Society Transactions

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

39

Aggregation of Engineered Human β-Cells Into Pseudoislets: Insulin Secretion and Gene Expression Profile in Normoxic and Hypoxic Milieu

Lecomte, Marie-José, Pechberty, Séverine, Machado, Cécile, Da Barroca, Sandra, Ravassard, Philippe, Scharfmann, Raphaël, Czernichow, Paul, Duvillié, Bertrand

Journal:

Year:

2016

Language:

english

File:

PDF, 960 KB

english, 2016

40

Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells

Chandra, Vikash, Karamitri, Angeliki, Richards, Paul, Cormier, Françoise, Ramond, Cyrille, Jockers, Ralf, Armanet, Mathieu, Albagli-Curiel, Olivier, Scharfmann, Raphael

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

41

EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium

Krizhanovskii, Camilla, Kristinsson, Hjalti, Elksnis, Andris, Wang, Xuan, Gavali, Hamid, Bergsten, Peter, Scharfmann, Raphael, Welsh, Nils

Journal:

Year:

2017

Language:

english

File:

PDF, 4.69 MB

english, 2017

42

Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2 + Human Pancreatic Progenitors

Ameri, Jacqueline, Borup, Rehannah, Prawiro, Christy, Ramond, Cyrille, Schachter, Karen A., Scharfmann, Raphael, Semb, Henrik

Journal:

Year:

2017

Language:

english

File:

PDF, 6.35 MB

english, 2017

43

Dédifférenciation de la cellule bêta pancréatique humaine

Diedisheim, Marc, Oshima, Masaya, Albagli, Olivier, Chimienti, Fabrice, Scharfmann, Raphaël

Journal:

Diabetes & Metabolism

Year:

2017

Language:

french

File:

PDF, 58 KB

french, 2017

44

Identification de 4 nouveaux gènes à risque de diabète de type 2 modulant la fonction β pancréatique et l’insulino-sécrétion

kiné Ndiaye, Fatou, Ortalli, Ana, Huyvaert, Marlène, Salazar-Cardozo, Clara, Canouil, Mickael, Kerr-Conte, Julie, Pattou, Francois, Marselli, Lorella, Marchetti, Piero, Scharfmann, Raphael, Froguel, P

Journal:

Diabetes & Metabolism

Year:

2017

Language:

french

File:

PDF, 71 KB

french, 2017

45

Mitochondrial Protein UCP2 Controls Pancreas Development

Broche, Benjamin, Ben Fradj, Selma, Aguilar, Esther, Sancerni, Tiphaine, Bénard, Matthieu, Makaci, Fatna, Berthault, Claire, Scharfmann, Raphaël, Alves-Guerra, Marie-Clotilde, Duvillié, Bertrand

Journal:

Year:

2017

Language:

english

File:

PDF, 3.62 MB

english, 2017

46

MondoA is an Essential Glucose Responsive Transcription Factor in Human Pancreatic Beta Cells.

Richards, Paul, Rachdi, Latif, Oshima, Masaya, Marchetti, Piero, Bugliani, Marco, Armanet, Mathieu, Postic, Catherine, Guilmeau, Sandra, Scharfmann, Raphael

Journal:

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

47

Cellules bêta pancréatiques

Ravassard, Philippe, Czernichow, Paul, Scharfmann, Raphaël

Journal:

médecine/sciences

Year:

2012

Language:

french

File:

PDF, 332 KB

french, 2012

48

Human Fucci Pancreatic Beta Cell Lines: New Tools to Study Beta Cell Cycle and Terminal Differentiation

Carlier, Géraldine, Maugein, Alicia, Cordier, Corinne, Pechberty, Séverine, Garfa-Traoré, Meriem, Martin, Patrick, Scharfmann, Raphaël, Albagli, Olivier, Rishi, Arun

Journal:

Year:

2014

Language:

english

File:

PDF, 2.78 MB

english, 2014

49

Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line

Andersson, Lotta E., Valtat, Bérengère, Bagge, Annika, Sharoyko, Vladimir V., Nicholls, David G., Ravassard, Philippe, Scharfmann, Raphael, Spégel, Peter, Mulder, Hindrik, Wagner, Bridget

Journal:

Year:

2015

Language:

english

File:

PDF, 2.30 MB

english, 2015

50

Solid-pseudopapillary neoplasms of the pancreas do not express major pancreatic markers in pediatric patients

Calvani, Julien, Lopez, Pauline, Sarnacki, Sabine, Molina, Thierry Jo, Gibault, Laure, Fabre, Monique, Scharfmann, Raphael, Capito, Carmen, Galmiche, Louise

Journal:

Human Pathology

Year:

2018

File:

PDF, 4.66 MB

2018